UniProt Q9H221
Q9H221
Q9H221 (UniProt Q9H221): 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H221
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
Structures
11 records of Q9H221 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DO7 | Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8 | x-ray diffraction | B, D | — | — |
| 5DO7 | Crystal structure of the human sterol transporter ABCG5/ABCG8 | x-ray diffraction | B, D | — | — |
| 7JR7 | Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4 | electron microscopy | B | — | — |
| 7R87 | The structure of human ABCG5-WT/ABCG8-I419E | electron microscopy | B | — | — |
| 7R88 | The structure of human ABCG5-I529W/ABCG8-wt | electron microscopy | B | — | — |
| 7R89 | The structure of human ABCG5/ABCG8 purified from yeast | electron microscopy | B | ERG | — |
| 7R89 | The structure of human ABCG5/ABCG8 purified from yeast | electron microscopy | B | ERG | — |
| 7R8A | The structure of human ABCG5/ABCG8 purified from mammalian cells | electron microscopy | B | CLR | — |
| 7R8B | The structure of human ABCG5/ABCG8 supplemented with cholesterol | electron microscopy | B | CLR | — |
| 8CUB | Crystal structure of ABCG5/G8 in complex with cholesterol | x-ray diffraction | D, B | CLR | — |
| Q9H221 | AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family G member 8 (Q9H221) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8CUB chain B against the predicted model Q9H221: TM-score 0.97, RMSD 1.66 Å
- 8CUB chain D against the predicted model Q9H221: TM-score 0.97, RMSD 1.66 Å
- 7JR7 chain B against the predicted model Q9H221: TM-score 0.97, RMSD 1.75 Å
- 7R89 chain B against the predicted model Q9H221: TM-score 0.97, RMSD 1.74 Å
- 7R89 chain B against the predicted model Q9H221: TM-score 0.97, RMSD 1.74 Å
- 7R8A chain B against the predicted model Q9H221: TM-score 0.97, RMSD 1.74 Å
- 7R8B chain B against the predicted model Q9H221: TM-score 0.96, RMSD 1.86 Å
- 7R88 chain B against the predicted model Q9H221: TM-score 0.96, RMSD 1.90 Å
- 7R87 chain B against the predicted model Q9H221: TM-score 0.96, RMSD 1.95 Å
- 5DO7 chain D against the predicted model Q9H221: TM-score 0.95, RMSD 1.88 Å
Elsewhere
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