MolNFT v2 · #185685 · protein
Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+/Ca2+
7LFX: “Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+/Ca2+”. Electron microscopy at 3.1, 2 ligands (PCG, CA). MolNFT v2 #185685 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LFX
- Type
- protein
- Length
- 1,800 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.1
- Source
- Homo sapiens
- UniProt
- P29973
- Ligands
- PCG, CA
Structure
electron microscopy · resolution 3.1 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 450 | — | P29973 |
Ligands and binding sites
- PCG · Cyclic guanosine monophosphate · ligand · 4 copies · chains A, B, C, D
- CA · Calcium ion · metal · 2 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7LFX · Cryo-EM structure of human cgmp-bound open CNGA1 channel in NA+/CA2+ · the same entry in another collection · chain D against D, TM-score 1.00
- P29973 · AlphaFold monomer V2.0 prediction for cgmp-gated cation channel alpha-1 (P29973) · a predicted model of the same protein · chain C against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29973
- Elsewhere: RCSB PDB 7LFX · PDBe 7LFX · UniProt P29973
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