MolNFT v2 · #183828 · protein
IPI-549 bound to the PI3Kg catalytic subunit p110 gamma
7JWZ: “IPI-549 bound to the PI3Kg catalytic subunit p110 gamma”. X-ray diffraction at 2.65, 1 ligand (V7Y). MolNFT v2 #183828 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7JWZ
- Type
- protein
- Length
- 832 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.65
- Source
- Homo sapiens
- UniProt
- P48736
- Ligands
- V7Y
Structure
x-ray diffraction · resolution 2.65 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 832 | — | P48736 |
Ligands and binding sites
- V7Y · 2-amino-N-[(1S)-1-{8-[(1-methyl-1H-pyrazol-4-yl) ethynyl]-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl}ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7JWZ · Ipi-549 bound to the PI3KG catalytic subunit P110 gamma · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P48736
- Elsewhere: RCSB PDB 7JWZ · PDBe 7JWZ · UniProt P48736
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