MolNFT v2 · #181119 · protein
Structure of liver pyruvate kinase in complex with allosteric modulator 41
7FSB: “Structure of liver pyruvate kinase in complex with allosteric modulator 41”. X-ray diffraction at 2.495, 5 ligands (OXL, OE0, FBP). MolNFT v2 #181119 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7FSB
- Type
- protein
- Length
- 3,405 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.495
- Source
- Homo sapiens
- UniProt
- P30613
- Ligands
- OXL, OE0, FBP, MG, K
Structure
x-ray diffraction · resolution 2.495 · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 422 | — | P30613 |
| B | — | protein | 436 | — | P30613 |
| C | — | protein | 425 | — | P30613 |
| D, H | — | protein | 425 | — | P30613 |
| E | — | protein | 419 | — | P30613 |
| F | — | protein | 432 | — | P30613 |
| G | — | protein | 421 | — | P30613 |
Ligands and binding sites
- OXL · Oxalate ion · ligand · 8 copies · chains A, B, C, D, E, F, G, H
- OE0 · N-({4-[(3,4-dihydroxyphenyl)methyl]phenyl}methyl)-3,4-dihydroxybenzene-1-sulfonamide · ligand · 4 copies · chains A, C, B, D, F, H, E, G
- FBP · 1,6-di-O-phosphono-beta-D-fructofuranose · sugar · 8 copies · chains A, B, C, G, D, E, F, H
- MG · Magnesium ion · metal · 8 copies · chains A, B, C, D, E, F, G, H
- K · Potassium ion · metal · 8 copies · chains A, B, C, D, E, F, G, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P30613
- Elsewhere: RCSB PDB 7FSB · PDBe 7FSB · UniProt P30613
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