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MolNFT v2 · #158083 · protein

Diheteromeric NMDA receptor GluN1/GluN2A in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4

6MMK: “Diheteromeric NMDA receptor GluN1/GluN2A in the '1-Knuckle' conformation, in complex with glycine and…”. Electron microscopy at 6.08, 1 ligand (NAG). MolNFT v2 #158083 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6MMK
Type
protein
Length
3,122 residues
Chains
4
Method
electron microscopy
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
6.08
Source
Rattus norvegicus
UniProt
P35439, Q00959
Ligands
NAG

Structure

electron microscopy · resolution 6.08 · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein782—P35439
B—protein772—Q00959
C—protein790—P35439
D—protein778—Q00959

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 40 copies · chains A, C, D, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6MMK · Diheteromeric NMDA receptor GLUN1/GLUN2A in the '1-knuckle' conformation, in complex with… · the same entry in another collection · chain D against D, TM-score 1.00
  • Q00959 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 2A (Q00959) · a predicted model of the same protein · chain D against A, TM-score 0.92
  • P35439 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 1 (P35439) · a predicted model of the same protein · chain C against A, TM-score 0.91

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