MolNFT v2 · #157533 · protein
Structure of human galectin-1 tandem-repeat mutant with lactose
6M5Y · Galectin-1,Galectin-1: “Structure of human galectin-1 tandem-repeat mutant with lactose”. X-ray diffraction at 1.38, 3 ligands (GAL, BGC, GLC), 1 pocket (best druggability 0.53). MolNFT v2 #157533 on GenesisL1: 3D structure, binding…
- PDB
- 6M5Y
- Type
- protein
- Length
- 270 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.38
- Source
- Homo sapiens
- Molecule
- Galectin-1,Galectin-1
- UniProt
- P09382
- Ligands
- GAL, BGC, GLC
- Pockets
- 1 · best druggability 0.53
Structure
x-ray diffraction · resolution 1.38 · 1 distinct chain · 1% helix, 60% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Galectin-1,Galectin-1 | protein | 270 | 1% helix, 60% strand | P09382 |
Ligands and binding sites
- GAL · beta-D-galactopyranose · sugar · 2 copies · chains A
- BGC · beta-D-glucopyranose · sugar · chains A
- GLC · alpha-D-glucopyranose · sugar · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 163 | 0.53 | 0.79 | 20 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09382
- Elsewhere: RCSB PDB 6M5Y · PDBe 6M5Y · UniProt P09382
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