UniProt P09382
Galectin-1 (P09382)
Galectin-1 (UniProt P09382): 71 experimental structures on GenesisL1, 15 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P09382
- Protein
- Galectin-1
- Experimental structures
- 71
- Predicted models
- 0
- Ligands
- 15
- Pockets
- 16 · 0 records with a druggable one
Structures
71 records of P09382 in the MolNFT archive: 71 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1GZW | X-ray crystal structure of human galectin-1 | x-ray diffraction | A, B | — | — |
| 1GZW | X-ray crystal structure of human galectin-1 | x-ray diffraction | A, B | — | — |
| 1W6M | X-ray crystal structure of C2S human galectin-1 complexed with galactose | x-ray diffraction | A, B | — | — |
| 1W6M | X-ray crystal structure of C2S human galectin-1 complexed with galactose | x-ray diffraction | A, B | — | — |
| 1W6N | X-ray crystal structure of C2S human galectin-1 | x-ray diffraction | A, B | — | — |
| 1W6N | X-ray crystal structure of C2S human galectin-1 | x-ray diffraction | A, B | — | — |
| 1W6O | X-ray crystal structure of C2S human galectin-1 complexed with lactose | x-ray diffraction | A, B | — | — |
| 1W6O | X-ray crystal structure of C2S human galectin-1 complexed with lactose | x-ray diffraction | A, B | — | — |
| 1W6P | X-RAY CRYSTAL STRUCTURE OF C2S HUMAN GALECTIN-1 COMPLEXED WITH N- Acetyl-LACTOSAMINE | x-ray diffraction | A, B | — | — |
| 1W6P | X-ray crystal structure of C2S human galectin-1 complexed with N- acetyl-lactosamine | x-ray diffraction | A, B | — | — |
| 1W6Q | X-ray crystal structure of R111H human galectin-1 | x-ray diffraction | A, B | — | — |
| 1W6Q | X-ray crystal structure of R111H human galectin-1 | x-ray diffraction | A, B | — | — |
| 2KM2 | Galectin-1 dimer | solution nmr | A, B | — | — |
| 2KM2 | Galectin-1 dimer | solution nmr | A, B | — | — |
| 2ZKN | X-ray structure of mutant galectin-1/lactose complex | x-ray diffraction | A, B | — | — |
| 2ZKN | X-ray structure of mutant galectin-1/LACTOSE complex | x-ray diffraction | A, B | — | — |
| 3OY8 | Crystal structure of human galectin-1 in complex with lactobionic acid | x-ray diffraction | A, B | — | — |
| 3OY8 | Crystal structure of human galectin-1 in complex with lactobionic acid | x-ray diffraction | A, B | — | — |
| 3OYW | Crystal structure of human galectin-1 in complex with thiodigalactoside | x-ray diffraction | A, B | — | — |
| 3OYW | Crystal structure of human galectin-1 in complex with thiodigalactoside | x-ray diffraction | A, B | — | — |
| 3T2T | Crystal structure of human galectin-1 in complex with methyl… | x-ray diffraction | A, B | — | — |
| 3T2T | Crystal structure of human galectin-1 in complex with methyl 2-O… | x-ray diffraction | A, B | — | — |
| 3W58 | Crystal structure of Galectin-1 in the lactose-unbound state(P21) | x-ray diffraction | A, B, C, D | — | — |
| 3W58 | Crystal structure of galectin-1 in the lactose-unbound STATE(P21) | x-ray diffraction | A, B, C, D | — | — |
| 3W59 | Crystal structure of Galectin-1 in the lactose-unbound state(P212121) | x-ray diffraction | A, B, C, D | — | — |
| 3W59 | Crystal structure of galectin-1 in the lactose-unbound STATE(P212121) | x-ray diffraction | A, B, C, D | — | — |
| 4Q1P | Galectin-1 in Complex with Ligand NB169 | x-ray diffraction | A, B | — | — |
| 4Q1P | Galectin-1 in complex with ligand NB169 | x-ray diffraction | A, B | — | — |
| 4Q1R | Galectin-1 in Complex with Ligand AN027 | x-ray diffraction | A, B | — | — |
| 4Q1R | Galectin-1 in complex with ligand AN027 | x-ray diffraction | A, B | — | — |
| 4Q26 | Crystal Structure of Galectin-1 in Complex with N-Acetyllactosamine | x-ray diffraction | A, B, G, H | — | — |
| 4Q26 | Crystal structure of galectin-1 in complex with N-acetyllactosamine | x-ray diffraction | A, B, G, H | — | — |
| 4Q27 | Galectin-1 in Complex with a Click-Activated N-Acetyllactosamine | x-ray diffraction | A, B | — | — |
| 4Q27 | Galectin-1 in complex with a click-activated N-acetyllactosamine | x-ray diffraction | A, B | — | — |
| 4Q2F | Galectin-1 in Complex with Ligand AN020 | x-ray diffraction | A, B | — | — |
| 4Q2F | Galectin-1 in complex with ligand AN020 | x-ray diffraction | A, B | — | — |
| 4XBL | Crystal Structure of Human Galectin-1 in Complex with Type 1 N-acetyllactosamine | x-ray diffraction | A, B | NAG, GAL | 2 (best 0.44) |
| 4XBL | Crystal structure of human galectin-1 in complex with type 1 N- acetyllactosamine | x-ray diffraction | A, B | — | — |
| 4Y1U | Complex of human Galectin-1 and Galbeta1-4GlcNAc | x-ray diffraction | B, A | — | — |
| 4Y1U | Complex of human galectin-1 and GALBETA1-4GLCNAC | x-ray diffraction | B, A | — | — |
| 4Y1V | Complex of human Galectin-1 and Galbeta1-3GlcNAc | x-ray diffraction | A, B | — | — |
| 4Y1V | Complex of human galectin-1 and GALBETA1-3GLCNAC | x-ray diffraction | A, B | — | — |
| 4Y1X | Complex of human Galectin-1 and Galbeta1-4(6OSO3)GlcNAc | x-ray diffraction | A, B | 6S2, GAL | 2 (best 0.39) |
| 4Y1X | Complex of human galectin-1 and GALBETA1-4(6OSO3)GLCNAC | x-ray diffraction | A, B | — | — |
| 4Y1Y | Complex of human Galectin-1 and (6OSO3)Galbeta1-3GlcNAc | x-ray diffraction | A, B | — | — |
| 4Y1Y | Complex of human galectin-1 and (6OSO3)GALBETA1-3GLCNAC | x-ray diffraction | A, B | — | — |
| 4Y1Z | Complex of human Galectin-1 and Galbeta1-4(6CO2)GlcNAc | x-ray diffraction | A, B | — | — |
| 4Y1Z | Complex of human galectin-1 and GALBETA1-4(6CO2)GLCNAC | x-ray diffraction | A, B | — | — |
| 4Y20 | Complex of human Galectin-1 and NeuAcalpha2-3Galbeta1-4Glc | x-ray diffraction | A, B | — | — |
| 4Y20 | Complex of human galectin-1 and NEUACALPHA2-3GALBETA1-4GLC | x-ray diffraction | A, B | — | — |
| 4Y22 | Complex of human Galectin-1 and (3OSO3)Galbeta1-3GlcNAc | x-ray diffraction | A, B | — | — |
| 4Y22 | Complex of human galectin-1 and (3OSO3)GALBETA1-3GLCNAC | x-ray diffraction | A, B | — | — |
| 4Y24 | Complex of human Galectin-1 and TD-139 | x-ray diffraction | A, B | TD2 | 2 (best 0.44) |
| 4Y24 | Complex of human galectin-1 and td-139 | x-ray diffraction | A, B | — | — |
| 5MWT | Galectin-1 in Complex with Ligand JB97 | x-ray diffraction | A, B | JB9, SO4 | — |
| 5MWT | Galectin-1 in complex with ligand JB97 | x-ray diffraction | A, B | JB9, SO4 | — |
| 5MWX | Galectin-1 in Complex with Ligand JB60 | x-ray diffraction | A, B | WYD, SO4 | 2 (best 0.47) |
| 5MWX | Galectin-1 in complex with ligand JB60 | x-ray diffraction | A, B | WYD, SO4 | — |
| 6B94 | Crystal structure of Human galectin-1 in complex with Lactulose | x-ray diffraction | A, B | FRU, GAL | — |
| 6B94 | Crystal structure of human galectin-1 in complex with lactulose | x-ray diffraction | A, B | FRU, GAL | — |
11 records more on the page itself.
Ligands
- GAL · beta-D-galactopyranose · in 6 records
- SO4 · Sulfate ion · in 6 records
- GLC · alpha-D-glucopyranose · in 4 records
- BGC · beta-D-glucopyranose · in 2 records
- FRU · beta-D-fructofuranose · in 2 records
- I7B · 4-amino-6-chlorobenzene-1,3-disulfonamide · in 2 records
- JB9 · ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-5-[(2~{S},3~{R}, 4~{S},5~{S},6~{R})-4-[[1-[[3-[(~{Z})-3-[bis(azanyl) methylideneamino]prop-1-enyl]phenyl]methyl]-1,2,3-triazol-4-yl]methoxy]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-6-(hydroxymethyl)-4-oxidanyl-2-prop-2-enoxy-oxan-3-yl]ethanamide · in 2 records
- WYD · ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-5-[(2~{S},3~{R}, 4~{S},5~{S},6~{R})-4-[[1-[[3-(3-azanylprop-1-ynyl) phenyl]methyl]-1,2,3-triazol-4-yl]methoxy]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-6-(hydroxymethyl)-4-oxidanyl-2-propoxy-oxan-3-yl]ethanamide · in 2 records
- 5KT · 3-deoxy-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-1-thio-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranoside · in 1 record
- 6S2 · methyl 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranoside · in 1 record
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
- OVD · ~{N}-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(hydroxymethyl)-5-[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,5-bis(oxidanyl)-4-(1~{H}-1,2,3-triazol-4-ylmethoxy)oxan-2-yl]oxy-4-oxidanyl-2-propoxy-oxan-3-yl]ethanamide · in 1 record
- TD2 · 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-3-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-1-thio-beta-D-galactopyranoside · in 1 record
- VPZ · (2~{R},3~{R},4~{S},5~{R},6~{R})-2-[3,5-bis(chloranyl)-4-fluoranyl-phenyl]sulfanyl-6-(hydroxymethyl)-4-[4-(1,3-thiazol-2-yl)-1,2,3-triazol-1-yl]oxane-3,5-diol · in 1 record
- YNO · 5-bromanyl-3-[(2~{R},3~{R},4~{S},5~{R},6~{R})-4-[4-(4-chloranyl-1,3-thiazol-2-yl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3-methoxy-5-oxidanyl-oxan-2-yl]sulfanyl-pyridine-2-carbonitrile · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.