MolNFT v2 · #157272 · protein + RNA
Pri-miRNA bound DROSHA-DGCR8 complex
6LXD: “Pri-miRNA bound DROSHA-DGCR8 complex”. Electron microscopy at 3.9, 1 ligand (ZN). MolNFT v2 #157272 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LXD
- Type
- protein + RNA
- Length
- 1,035 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.9
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- Q9NRR4, Q8WYQ5
- Ligands
- ZN
Structure
electron microscopy · resolution 3.9 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 918 | — | Q9NRR4 |
| B | — | protein | 24 | — | Q8WYQ5 |
| C | — | protein | 21 | — | Q8WYQ5 |
| D | — | rna | 72 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6LXD · Pri-miRNA bound drosha-DGCR8 complex · the same entry in another collection · chain A against A, TM-score 1.00
- Q9NRR4 · AlphaFold monomer V2.0 prediction for ribonuclease 3 (Q9NRR4) · a predicted model of the same protein · chain A against A, TM-score 0.97
- Q8WYQ5 · AlphaFold monomer V2.0 prediction for microprocessor complex subunit DGCR8 (Q8WYQ5) · a predicted model of the same protein · chain B against A, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NRR4
- Every structure of UniProt Q8WYQ5
- Elsewhere: RCSB PDB 6LXD · PDBe 6LXD · UniProt Q9NRR4 · UniProt Q8WYQ5
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