MolNFT v2 · #156613 · protein
Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009
6LCB: “Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009”. X-ray diffraction at 1.4, 2 ligands (E83, SO4). MolNFT v2 #156613 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LCB
- Type
- protein
- Length
- 82 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.4
- Source
- Homo sapiens
- UniProt
- O14640
- Ligands
- E83, SO4
Structure
x-ray diffraction · resolution 1.4 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 82 | — | O14640 |
Ligands and binding sites
- E83 · 2-[[3-[(2E)-2-[1,3-bis(oxidanylidene)-1-phenyl-butan-2-ylidene]hydrazinyl]phenyl]sulfonylamino]benzoic acid · ligand · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6LCB · Crystal structure of human DISHEVELLED1 PDZ domain with its inhibitor NPL3009 · the same entry in another collection · chain A against A, TM-score 1.00
- O14640 · AlphaFold monomer V2.0 prediction for segment polarity protein dishevelled homolog dvl-1… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14640
- Elsewhere: RCSB PDB 6LCB · PDBe 6LCB · UniProt O14640
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