UniProt O14640
O14640
O14640 (UniProt O14640): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14640
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
Structures
5 records of O14640 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LCA | Crystal structure of human Dishevelled1 PDZ domain homotrimer | x-ray diffraction | A, B, C, D, E, F, G, H | SO4 | — |
| 6LCA | Crystal structure of human DISHEVELLED1 PDZ domain homotrimer | x-ray diffraction | A, B, C, D, E, F, G, H | SO4 | — |
| 6LCB | Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009 | x-ray diffraction | A | E83, SO4 | — |
| 6LCB | Crystal structure of human DISHEVELLED1 PDZ domain with its inhibitor NPL3009 | x-ray diffraction | A | E83, SO4 | — |
| O14640 | AlphaFold monomer V2.0 prediction for segment polarity protein dishevelled homolog dvl-1 (O14640) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6LCB chain A against the predicted model O14640: TM-score 0.96, RMSD 0.69 Å
- 6LCB chain A against the predicted model O14640: TM-score 0.96, RMSD 0.69 Å
- 6LCA chain A against the predicted model O14640: TM-score 0.94, RMSD 1.18 Å
- 6LCA chain A against the predicted model O14640: TM-score 0.94, RMSD 1.18 Å
- 6LCA chain B against the predicted model O14640: TM-score 0.92, RMSD 1.71 Å
- 6LCA chain B against the predicted model O14640: TM-score 0.92, RMSD 1.71 Å
- 6LCA chain D against the predicted model O14640: TM-score 0.92, RMSD 1.59 Å
- 6LCA chain D against the predicted model O14640: TM-score 0.92, RMSD 1.59 Å
- 6LCA chain H against the predicted model O14640: TM-score 0.92, RMSD 1.81 Å
- 6LCA chain H against the predicted model O14640: TM-score 0.92, RMSD 1.81 Å
Elsewhere
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