MolNFT v2 · #155908 · protein

Crystal structure of an agonist bound GPCR

6KPC: “Crystal structure of an agonist bound GPCR”. X-ray diffraction at 3.2, 1 ligand (E3R). MolNFT v2 #155908 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6KPC
Type: protein
Length: 445 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 3.2
Source: Enterobacteria phage RB59; Homo sapiens
UniProt: P34972, A0A097J809
Ligands: E3R

Structure

x-ray diffraction · resolution 3.2 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	445	—	P34972, A0A097J809

Ligands and binding sites

E3R · 7-[(6aR,9R,10aR)-1-Hydroxy-9-(hydroxymethyl)-6,6-dimethyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-3-yl]- 7-methyloctanenitrile · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6KPC · Crystal structure of an agonist bound GPCR · the same entry in another collection · chain A against A, TM-score 1.00
P34972 · AlphaFold monomer V2.0 prediction for cannabinoid receptor 2 (P34972) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P34972
Every structure of UniProt A0A097J809
Elsewhere: RCSB PDB 6KPC · PDBe 6KPC · UniProt P34972 · UniProt A0A097J809

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