MolNFT v2 · #155865 · protein
THRb mutation with a novel agonist
6KNU: “THRb mutation with a novel agonist”. X-ray diffraction at 2.7, 1 ligand (8HO). MolNFT v2 #155865 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6KNU
- Type
- protein
- Length
- 251 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.7
- Source
- Homo sapiens
- UniProt
- P10828, Q15596
- Ligands
- 8HO
Structure
x-ray diffraction · resolution 2.7 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 242 | — | P10828 |
| C | — | protein | 9 | — | Q15596 |
Ligands and binding sites
- 8HO · 2-[(1-methyl-4-oxidanyl-7-phenoxy-isoquinolin-3-yl) carbonylamino]ethanoic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6KNU · Thrb mutation with a novel agonist · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P10828
- Every structure of UniProt Q15596
- Elsewhere: RCSB PDB 6KNU · PDBe 6KNU · UniProt P10828 · UniProt Q15596
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