GL1X · GenesisL1 explorer

MolNFT v2 · #155399 · protein

Human LXR-beta in complex with an agonist

6K9H: “Human LXR-beta in complex with an agonist”. X-ray diffraction at 2.5, 1 ligand (D40). MolNFT v2 #155399 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6K9H
Type
protein
Length
454 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
2.5
Source
Homo sapiens
UniProt
P55055
Ligands
D40

Structure

x-ray diffraction · resolution 2.5 · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein227—P55055
B—protein227—P55055

Ligands and binding sites

  • D40 · ~{tert}-butyl (2'~{S},3~{S})-2-oxidanylidene-2'-phenyl-spiro[1~{H}-indole-3,3'-pyrrolidine]-1'-carboxylate · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6K9H · Human lxr-beta in complex with an agonist · the same entry in another collection · chain A against A, TM-score 1.00
  • P55055 · AlphaFold monomer V2.0 prediction for oxysterols receptor lxr-beta (P55055) · a predicted model of the same protein · chain A against A, TM-score 0.94

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