MolNFT v2 · #154881 · protein
Structure of human soluble guanylate cyclase in the unliganded state
6JT0: “Structure of human soluble guanylate cyclase in the unliganded state”. Electron microscopy at 4.0, 1 ligand (HEM). MolNFT v2 #154881 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6JT0
- Type
- protein
- Length
- 1,118 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.0
- Source
- Homo sapiens
- UniProt
- Q02108, Q02153
- Ligands
- HEM
Structure
electron microscopy · resolution 4.0 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 542 | — | Q02108 |
| B | — | protein | 576 | — | Q02153 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6JT0 · Structure of human soluble guanylate cyclase in the unliganded state · the same entry in another collection · chain A against A, TM-score 1.00
- Q02108 · AlphaFold monomer V2.0 prediction for guanylate cyclase soluble subunit alpha-1 (Q02108) · a predicted model of the same protein · chain A against A, TM-score 0.54
- Q02153 · AlphaFold monomer V2.0 prediction for guanylate cyclase soluble subunit beta-1 (Q02153) · a predicted model of the same protein · chain B against A, TM-score 0.45
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02108
- Every structure of UniProt Q02153
- Elsewhere: RCSB PDB 6JT0 · PDBe 6JT0 · UniProt Q02108 · UniProt Q02153
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