MolNFT v2 · #153958 · protein

E. coli methionine aminopeptidase crystal structure fitted into the cryo-EM density map of E. coli 70S ribosome in complex with methionine aminopeptidase

6IZ7: “E. coli methionine aminopeptidase crystal structure fitted into the cryo-EM density map of E. coli 70S…”. Electron microscopy at 11.8, 4 pockets (best druggability 0.47). MolNFT v2 #153958 on GenesisL1: 3D structure, binding sites…

PDB: 6IZ7
Type: protein
Length: 262 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 11.8
Source: Escherichia coli K-12
Molecule: Methionine aminopeptidase
EC: 3.4.11.18
UniProt: P0AE18
Pockets: 4 · best druggability 0.47

Structure

electron microscopy · resolution 11.8 · 1 distinct chain · 0% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
P	Methionine aminopeptidase (EC 3.4.11.18)	protein	262	0% helix, 0% strand	P0AE18

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	202	0.47	0.73	54	empty
2	92	0.36	0.73	35	empty
3	82	0.34	0.73	28	empty
4	52	0.27	0.72	21	empty

Compared structures

6IZ7 · E. COLI methionine aminopeptidase crystal structure fitted into the cryo-EM density MAP… · the same entry in another collection · chain P against P, TM-score 1.00
P0AE18 · AlphaFold monomer V2.0 prediction for methionine aminopeptidase (P0AE18) · a predicted model of the same protein · chain P against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0AE18
Elsewhere: RCSB PDB 6IZ7 · PDBe 6IZ7 · UniProt P0AE18

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