MolNFT v2 · #129940 · protein + RNA
Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation
5ON2: “Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate…”. X-ray diffraction at 3.1, 3 ligands (LSS, ZN, MG). MolNFT v2 #129940 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5ON2
- Type
- protein + RNA
- Length
- 1,889 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.1
- Source
- Escherichia coli (strain K12); SYNTHETIC CONSTRUCT
- UniProt
- P07813
- Ligands
- LSS, ZN, MG
Structure
x-ray diffraction · resolution 3.1 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 863 | — | P07813 |
| B | — | rna | 85 | — | — |
| D | — | protein | 861 | — | P07813 |
| E | — | rna | 80 | — | — |
Ligands and binding sites
- LSS · 5'-O-(L-leucylsulfamoyl)adenosine · ligand · 2 copies · chains A, B, D, E
- ZN · Zinc ion · metal · 2 copies · chains A, D
- MG · Magnesium ion · metal · 2 copies · chains B, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5ON2 · Quaternary complex of mutant T252A of E. COLI leucyl-tRNA synthetase with TRNA(LEU)… · the same entry in another collection · chain A against A, TM-score 1.00
- P07813 · AlphaFold monomer V2.0 prediction for leucine--tRNA ligase (P07813) · a predicted model of the same protein · chain D against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07813
- Elsewhere: RCSB PDB 5ON2 · PDBe 5ON2 · UniProt P07813
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