MolNFT v2 · #128115 · protein
Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and fragment like molekule 2-cyclopropyl-4,5-dimethylthieno[5,4-d]pyrimidine-6-carboxylic acid
5N4V: “Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and fragment like molekule…”. X-ray diffraction at 1.85, 1 ligand (8MW). MolNFT v2 #128115 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5N4V
- Type
- protein
- Length
- 282 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.85
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- P11309
- Ligands
- 8MW
Structure
x-ray diffraction · resolution 1.85 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 273 | — | P11309 |
| D | — | protein | 9 | — | — |
Ligands and binding sites
- 8MW · 2-cyclopropyl-4,5-dimethyl-thieno[2,3-d]pyrimidine-6-carboxylic acid · ligand · chains A
- GOL · Glycerol · additive · chains A, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5N4V · Crystal structure of human pim-1 kinase in complex with a consensuspeptide and fragment… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11309
- Elsewhere: RCSB PDB 5N4V · PDBe 5N4V · UniProt P11309
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.