MolNFT v1 · #127718 · protein
Crystal structure of human pim-1 kinase in complex with a consensuspeptide and fragment like molekule 2-cyclopropyl-4,5- DIMETHYLTHIENO[5,4-D]PYRIMIDINE-6-carboxylic acid
5N4V: “Crystal structure of human pim-1 kinase in complex with a consensuspeptide and fragment like molekule…”. X-ray diffraction, 1 ligand (8MW). MolNFT v1 #127718 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5N4V
- Type
- protein
- Length
- 282 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P11309
- Ligands
- 8MW
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 273 | — | P11309 |
| D | — | protein | 9 | — | — |
Ligands and binding sites
- 8MW · 2-cyclopropyl-4,5-dimethyl-thieno[2,3-d]pyrimidine-6-carboxylic acid · ligand · chains A
- GOL · Glycerol · additive · chains A, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5N4V · Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and fragment… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11309
- Elsewhere: RCSB PDB 5N4V · PDBe 5N4V · UniProt P11309
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