MolNFT v2 · #116923 · protein
Structure of WT Human Glutathione Transferase in complex with cisplatin in the presence of glutathione.
5DJL: “Structure of WT Human Glutathione Transferase in complex with cisplatin in the presence of glutathione.”. X-ray diffraction at 1.8, 5 ligands (GSH, PT, CA). MolNFT v2 #116923 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 5DJL
- Type
- protein
- Length
- 419 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.8
- Source
- Homo sapiens
- UniProt
- P09211
- Ligands
- GSH, PT, CA, CO3, SO4
Structure
x-ray diffraction · resolution 1.8 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 210 | — | P09211 |
| B | — | protein | 209 | — | P09211 |
Ligands and binding sites
- GSH · Glutathione · ligand · 2 copies · chains A, B
- PT · Platinum (II) ion · metal · 3 copies · chains A, B
- CA · Calcium ion · metal · 2 copies · chains B
- CO3 · Carbonate ion · ion · chains B
- SO4 · Sulfate ion · ion · chains B
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5DJL · Structure of wt human glutathione transferase in complex with cisplatin in the presence… · the same entry in another collection · chain A against A, TM-score 1.00
- P09211 · AlphaFold monomer V2.0 prediction for glutathione S-transferase P (P09211) · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09211
- Elsewhere: RCSB PDB 5DJL · PDBe 5DJL · UniProt P09211
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.