MolNFT v1 · #90640 · protein
The crystal structure of the ferric yersiniabactin uptake receptor fyua from yersinia pestis
4EPA · Pesticin receptor: “The crystal structure of the ferric yersiniabactin uptake receptor fyua from yersinia pestis”. X-ray diffraction, 4 pockets (best druggability 0.88). MolNFT v1 #90640 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4EPA
- Type
- protein
- Length
- 632 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pesticin receptor
- UniProt
- P46359
- Pockets
- 4 · best druggability 0.88
Structure
x-ray diffraction · 1 distinct chain · 3% helix, 59% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pesticin receptor | protein | 632 | 3% helix, 59% strand | P46359 |
Ligands and binding sites
- LDA · Lauryl dimethylamine-N-oxide · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1195 | 0.88 | 0.90 | 149 | empty |
| 2 | 863 | 0.79 | 0.82 | 94 | empty |
| 3 | 565 | 0.77 | 0.84 | 62 | empty |
| 4 | 65 | 0.53 | 0.87 | 17 | empty |
Modifications
Observed in the structure: 15 modified (engineered).
Compared structures
- 4EPA · The crystal structure of the ferric yersiniabactin uptake receptor FyuA from Yersinia… · the same entry in another collection · chain A against A, TM-score 1.00
- P46359 · AlphaFold monomer V2.0 prediction for pesticin receptor (P46359) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P46359
- Elsewhere: RCSB PDB 4EPA · PDBe 4EPA · UniProt P46359
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