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MolNFT v1 · #88014 · protein

Structure of the DDB1-crbn E3 ubiquitin ligase bound to pomalidomide

4CI3: “Structure of the DDB1-crbn E3 ubiquitin ligase bound to pomalidomide”. X-ray diffraction. MolNFT v1 #88014 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
4CI3
Type
protein
Length
1,461 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q16531, P0CF65

Structure

x-ray diffraction · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein1091—Q16531
B—protein370—P0CF65

Compared structures

  • 4CI3 · Structure of the DDB1-CRBN E3 ubiquitin ligase bound to Pomalidomide · the same entry in another collection · chain A against A, TM-score 1.00
  • P0CF65 · AlphaFold monomer V2.0 prediction for protein cereblon (P0CF65) · a predicted model of the same protein · chain B against A, TM-score 0.99
  • Q16531 · AlphaFold monomer V2.0 prediction for DNA damage-binding protein 1 (Q16531) · a predicted model of the same protein · chain A against A, TM-score 0.96

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