UniProt P0CF65
P0CF65
P0CF65 (UniProt P0CF65): 6 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P0CF65
- Experimental structures
- 6
- Predicted models
- 1
Structures
7 records of P0CF65 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4CI1 | Structure of the DDB1-CRBN E3 ubiquitin ligase bound to thalidomide | x-ray diffraction | B | — | — |
| 4CI1 | Structure of the DDB1-crbn E3 ubiquitin ligase bound to thalidomide | x-ray diffraction | B | — | — |
| 4CI2 | Structure of the DDB1-CRBN E3 ubiquitin ligase bound to lenalidomide | x-ray diffraction | B | — | — |
| 4CI2 | Structure of the DDB1-crbn E3 ubiquitin ligase bound to lenalidomide | x-ray diffraction | B | — | — |
| 4CI3 | Structure of the DDB1-CRBN E3 ubiquitin ligase bound to Pomalidomide | x-ray diffraction | B | — | — |
| 4CI3 | Structure of the DDB1-crbn E3 ubiquitin ligase bound to pomalidomide | x-ray diffraction | B | — | — |
| P0CF65 | AlphaFold monomer V2.0 prediction for protein cereblon (P0CF65) | predicted | A | — | — |
Experiment against prediction
- 4CI3 chain B against the predicted model P0CF65: TM-score 0.99, RMSD 0.72 Å
- 4CI3 chain B against the predicted model P0CF65: TM-score 0.99, RMSD 0.72 Å
- 4CI2 chain B against the predicted model P0CF65: TM-score 0.99, RMSD 0.73 Å
- 4CI2 chain B against the predicted model P0CF65: TM-score 0.99, RMSD 0.73 Å
- 4CI1 chain B against the predicted model P0CF65: TM-score 0.99, RMSD 0.74 Å
- 4CI1 chain B against the predicted model P0CF65: TM-score 0.99, RMSD 0.74 Å
Elsewhere
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