MolNFT v1 · #87401 · protein
Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with CACL2 at 1.5 ångströms
4C07 · Protein arginine N-methyltransferase 6: “Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with CACL2 at 1.5 ångströms”. X-ray diffraction, 1 ligand (CA), 2 pockets (best druggability 0.60). MolNFT v1 #87401…
- PDB
- 4C07
- Type
- protein
- Length
- 326 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein arginine N-methyltransferase 6
- EC
- 2.1.1.-, 2.1.1.125
- UniProt
- Q6NZB1
- Ligands
- CA
- Pockets
- 2 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 28% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein arginine N-methyltransferase 6 (EC 2.1.1.-, 2.1.1.125) | protein | 326 | 28% helix, 35% strand | Q6NZB1 |
Ligands and binding sites
- CA · Calcium ion · metal · 6 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 274 | 0.60 | 0.79 | 37 | CA |
| 2 | 100 | 0.50 | 0.81 | 17 | empty |
Compared structures
- 4C07 · Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with CaCl2 at… · the same entry in another collection · chain A against A, TM-score 1.00
- Q6NZB1 · AlphaFold monomer V2.0 prediction for protein arginine N-methyltransferase 6 (Q6NZB1) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6NZB1
- Elsewhere: RCSB PDB 4C07 · PDBe 4C07 · UniProt Q6NZB1
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