Structure of the lectin bambl from burkholderia ambifaria in complex with blood group H type 1 tetrasaccharide

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 68% strand (DSSP).

Ligands and binding sites

• GAL · beta-D-galactopyranose · sugar · 6 copies · chains A, B, C
• FUC · alpha-L-fucopyranose · sugar · 6 copies · chains A, B, C
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 5 copies · chains A, B, C
• GLA · alpha-D-galactopyranose · sugar · chains C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Interfaces

3 interfaces between chains.

• A–C · 729 Ų buried · 8 hydrogen bonds · protein-protein
• B–C · 713 Ų buried · 9 hydrogen bonds · protein-protein
• A–B · 706 Ų buried · 9 hydrogen bonds · protein-protein

Compared structures

• 3ZW2 · Structure of the lectin Bambl from Burkholderia ambifaria in complex with blood group H… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q0B4G1
• Elsewhere: RCSB PDB 3ZW2 · PDBe 3ZW2 · UniProt Q0B4G1