MolNFT v1 · #82663 · protein
Crystal structure of optineurin lir-fused human LC3B_2-119
3VTV · Optineurin, microtubule-associated proteins 1A/1B light…: “Crystal structure of optineurin lir-fused human LC3B_2-119”. X-ray diffraction, 1 ligand (SO4), 1 pocket (best druggability 0.42). MolNFT v1 #82663 on GenesisL1: 3D…
- PDB
- 3VTV
- Type
- protein
- Length
- 125 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Optineurin, microtubule-associated proteins 1A/1B light chain 3B
- UniProt
- Q96CV9, Q9GZQ8
- Ligands
- SO4
- Pockets
- 1 · best druggability 0.42
Structure
x-ray diffraction · 1 distinct chain · 30% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Optineurin, microtubule-associated proteins 1A/1B light chain 3B | protein | 125 | 30% helix, 22% strand | Q96CV9, Q9GZQ8 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 128 | 0.42 | 0.76 | 25 | empty |
Compared structures
- 3VTV · Crystal structure of Optineurin LIR-fused human LC3B_2-119 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9GZQ8 · AlphaFold monomer V2.0 prediction for microtubule-associated proteins 1A/1B light chain… · a predicted model of the same protein · chain A against A, TM-score 0.88
- Q96CV9 · AlphaFold monomer V2.0 prediction for optineurin (Q96CV9) · a predicted model of the same protein · chain A against A, TM-score 0.21
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96CV9
- Every structure of UniProt Q9GZQ8
- Elsewhere: RCSB PDB 3VTV · PDBe 3VTV · UniProt Q96CV9 · UniProt Q9GZQ8
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