UniProt Q96CV9
Optineurin (Q96CV9)
Optineurin (UniProt Q96CV9): 21 experimental structures on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q96CV9
- Protein
- Optineurin
- Experimental structures
- 21
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
21 records of Q96CV9 in the MolNFT archive: 21 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LO4 | NMR Solution Structure of Optineurin Zinc-finger Domain | solution nmr | A | — | — |
| 2LO4 | NMR solution structure of optineurin zinc-finger domain | solution nmr | A | — | — |
| 2LUE | LC3B OPTN-LIR Ptot complex structure | solution nmr | B | — | — |
| 2LUE | LC3B optn-lir ptot complex structure | solution nmr | B | — | — |
| 3VTV | Crystal structure of Optineurin LIR-fused human LC3B_2-119 | x-ray diffraction | A | — | — |
| 3VTV | Crystal structure of optineurin lir-fused human LC3B_2-119 | x-ray diffraction | A | — | — |
| 3VTW | Crystal structure of T7-tagged Optineurin LIR-fused human LC3B_2-119 | x-ray diffraction | A, B, C | — | — |
| 3VTW | Crystal structure of T7-tagged optineurin lir-fused human LC3B_2-119 | x-ray diffraction | A, B, C | — | — |
| 5AAZ | TBK1 recruitment to cytosol-invading Salmonella induces anti- bacterial autophagy | solution nmr | A | ZN | — |
| 5AAZ | TBK1 recruitment to cytosol-invading salmonella induces anti-bacterial autophagy | solution nmr | A | — | — |
| 5B83 | Crystal structure of Optineurin UBAN in complex with linear ubiquitin | x-ray diffraction | B, C, E, F | — | — |
| 5B83 | Crystal structure of optineurin uban in complex with linear ubiquitin | x-ray diffraction | B, C, E, F | — | — |
| 5EOA | Crystal structure of OPTN E50K mutant and TBK1 complex | x-ray diffraction | A, B | — | — |
| 5EOA | Crystal structure of optn E50K mutant and TBK1 complex | x-ray diffraction | A, B | — | — |
| 5EOF | Crystal structure of OPTN NTD and TBK1 CTD complex | x-ray diffraction | A, B | — | — |
| 5EOF | Crystal structure of optn ntd and TBK1 ctd complex | x-ray diffraction | A, B | — | — |
| 7CZM | Crystal structure of FIP200 Claw/p-OPtineurin LIR complex | x-ray diffraction | C, D | — | — |
| 7CZM | Crystal structure of FIP200 CLAW/P-optineurin lir complex | x-ray diffraction | C, D | — | — |
| 9B0B | Structure of Optineurin bound to HOIP NZF1 domain | x-ray diffraction | A, B, C, D | — | 2 (best 0.45) |
| 9IKQ | Crystal structure of OPTN LZD in complex with GTP-bound Rab8a(Q67L) | x-ray diffraction | C, D | — | 4 (best 0.62) |
| Q96CV9 | AlphaFold monomer V2.0 prediction for optineurin (Q96CV9) | — | — | — |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 3VTV chain A against the predicted model Q9GZQ8: TM-score 0.88, RMSD 1.67 Å
- 3VTV chain A against the predicted model Q9GZQ8: TM-score 0.88, RMSD 1.67 Å
- 3VTW chain A against the predicted model Q9GZQ8: TM-score 0.88, RMSD 1.60 Å
- 3VTW chain A against the predicted model Q9GZQ8: TM-score 0.88, RMSD 1.60 Å
Elsewhere
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