MolNFT v1 · #82223 · protein

Iodide derivative of human lfabp

3VG2 · Fatty acid-binding protein, liver: “Iodide derivative of human lfabp”. X-ray diffraction, 2 ligands (PLM, IOD), 1 pocket (best druggability 0.84). MolNFT v1 #82223 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3VG2
Type: protein
Length: 129 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fatty acid-binding protein, liver
UniProt: P07148
Ligands: PLM, IOD
Pockets: 1 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 60% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fatty acid-binding protein, liver	protein	129	12% helix, 60% strand	P07148

Ligands and binding sites

PLM · Palmitic acid · ligand · 2 copies · chains A
IOD · Iodide ion · ion · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	396	0.84	0.91	50	PLM, IOD

Compared structures

3VG2 · Iodide derivative of human LFABP · the same entry in another collection · chain A against A, TM-score 1.00
P07148 · AlphaFold monomer V2.0 prediction for fatty acid-binding protein, liver (P07148) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07148
Elsewhere: RCSB PDB 3VG2 · PDBe 3VG2 · UniProt P07148

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