MolNFT v1 · #81619 · protein
The 3-mbt repeat domain of L3MBTL1 in complex with a methyl-lysine mimic
3UWN · LETHAL(3)MALIGNANT brain tumor-like protein 1: “The 3-mbt repeat domain of L3MBTL1 in complex with a methyl-lysine mimic”. X-ray diffraction, 2 ligands (UWN, UNX), 1 pocket (best druggability 0.72). MolNFT v1 #81619 on GenesisL1: 3D…
- PDB
- 3UWN
- Type
- protein
- Length
- 318 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- LETHAL(3)MALIGNANT brain tumor-like protein 1
- UniProt
- Q9Y468
- Ligands
- UWN, UNX
- Pockets
- 1 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 20% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | LETHAL(3)MALIGNANT brain tumor-like protein 1 | protein | 318 | 20% helix, 30% strand | Q9Y468 |
Ligands and binding sites
- UWN · [2-(phenylamino)benzene-1,4-diyl]bis{[4-(pyrrolidin-1-yl)piperidin-1-yl]methanone} · ligand · chains A
- UNX · Unknown atom or ion · ion · 14 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 769 | 0.72 | 0.78 | 60 | UNX |
Compared structures
- 3UWN · The 3-MBT repeat domain of L3MBTL1 in complex with a methyl-lysine mimic · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y468 · AlphaFold monomer V2.0 prediction for LETHAL(3)MALIGNANT brain tumor- like protein 1… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y468
- Elsewhere: RCSB PDB 3UWN · PDBe 3UWN · UniProt Q9Y468
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