MolNFT v1 · #79179 · protein
Human MPP8 - human DNMT3AK47ME2 peptide
3SVM · M-phase phosphoprotein 8: “Human MPP8 - human DNMT3AK47ME2 peptide”. X-ray diffraction. MolNFT v1 #79179 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3SVM
- Type
- protein
- Length
- 72 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- M-phase phosphoprotein 8; DNA (cytosine-5)-methyltransferase 3A
- EC
- 2.1.1.37
- UniProt
- Q99549, Q9Y6K1
Structure
x-ray diffraction · 2 distinct chains · 25% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | M-phase phosphoprotein 8 | protein | 60 | 30% helix, 40% strand | Q99549 |
| P | DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) | protein | 12 | 0% helix, 17% strand | Q9Y6K1 |
Interfaces
1 interface between chains.
- A–P · 688 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (methylation).
Compared structures
- 3SVM · Human MPP8 - human DNMT3AK47me2 peptide · the same entry in another collection · chain A against A, TM-score 1.00
- Q99549 · AlphaFold monomer V2.0 prediction for M-phase phosphoprotein 8 (Q99549) · a predicted model of the same protein · chain A against A, TM-score 0.87
- Q9Y6K1 · AlphaFold monomer V2.0 prediction for DNA (cytosine-5)-methyltransferase 3A (Q9Y6K1) · a predicted model of the same protein · chain P against A, TM-score 0.37
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99549
- Every structure of UniProt Q9Y6K1
- Elsewhere: RCSB PDB 3SVM · PDBe 3SVM · UniProt Q99549 · UniProt Q9Y6K1
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