MolNFT v1 · #76449 · protein
Monoclinic complex structure of atrx add bound to histone H3K9ME3 peptide
3QL9 · Transcriptional regulator atrx: “Monoclinic complex structure of atrx add bound to histone H3K9ME3 peptide”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #76449 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3QL9
- Type
- protein
- Length
- 135 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator atrx; Peptide of histone H3.3
- EC
- 3.6.4.12
- UniProt
- P46100, P84243
- Ligands
- ZN
Structure
x-ray diffraction · 2 distinct chains · 27% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator atrx (EC 3.6.4.12) | protein | 125 | 30% helix, 15% strand | P46100 |
| C | Peptide of histone H3.3 | protein | 10 | 0% helix, 30% strand | P84243 |
Ligands and binding sites
- ZN · Zinc ion · metal · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–C · 716 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (methylation).
Compared structures
- 3QL9 · Monoclinic complex structure of ATRX ADD bound to histone H3K9me3 peptide · the same entry in another collection · chain A against A, TM-score 1.00
- P46100 · AlphaFold monomer V2.0 prediction for transcriptional regulator atrx (P46100) · a predicted model of the same protein · chain A against A, TM-score 0.94
- P84243 · AlphaFold monomer V2.0 prediction for histone H3.3 (P84243) · a predicted model of the same protein · chain C against A, TM-score 0.39
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P46100
- Every structure of UniProt P84243
- Elsewhere: RCSB PDB 3QL9 · PDBe 3QL9 · UniProt P46100 · UniProt P84243
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