MolNFT v1 · #75849 · protein

Mouse E-cadherin EC1-2 L175D mutant

3Q2N · Cadherin-1: “Mouse E-cadherin EC1-2 L175D mutant”. X-ray diffraction, 1 ligand (CA). MolNFT v1 #75849 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3Q2N
Type: protein
Length: 426 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cadherin-1
UniProt: P09803
Ligands: CA

Structure

x-ray diffraction · 1 distinct chain · 1% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Cadherin-1	protein	213	1% helix, 44% strand	P09803

Ligands and binding sites

CA · Calcium ion · metal · 8 copies · chains A, B
PG4 · Tetraethylene glycol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 926 Å² buried · 20 hydrogen bonds · protein-protein

Compared structures

3Q2N · Mouse E-cadherin EC1-2 L175D mutant · the same entry in another collection · chain A against A, TM-score 1.00
P09803 · AlphaFold monomer V2.0 prediction for cadherin-1 (P09803) · a predicted model of the same protein · chain B against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09803
Elsewhere: RCSB PDB 3Q2N · PDBe 3Q2N · UniProt P09803

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