UniProt P09803
Cadherin-1 (P09803)
Cadherin-1 (UniProt P09803): 39 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P09803
- Protein
- Cadherin-1
- Experimental structures
- 39
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
40 records of P09803 in the MolNFT archive: 39 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EDH | E-cadherin domains 1 and 2 in complex with calcium | x-ray diffraction | A, B | — | — |
| 1EDH | E-cadherin domains 1 and 2 in complex with calcium | x-ray diffraction | A, B | — | — |
| 1FF5 | Structure of E-cadherin double domain | x-ray diffraction | A, B | — | — |
| 1FF5 | Structure of E-cadherin double domain | x-ray diffraction | A, B | — | — |
| 1I7W | Beta-CATENIN/PHOSPHORYLATED E-cadherin complex | x-ray diffraction | B, D | — | — |
| 1I7W | Beta-CATENIN/PHOSPHORYLATED E-cadherin complex | x-ray diffraction | B, D | — | — |
| 1I7X | Beta-CATENIN/E-cadherin complex | x-ray diffraction | B, D | — | — |
| 1I7X | Beta-CATENIN/E-cadherin complex | x-ray diffraction | B, D | — | — |
| 1Q1P | E-Cadherin activation | x-ray diffraction | A | — | — |
| 1Q1P | E-cadherin activation | x-ray diffraction | A | — | — |
| 1SUH | Amino-terminal domain of epithelial cadherin in the calcium bound state, NMR, 20 structures | solution nmr | A | — | — |
| 1SUH | Amino-terminal domain of epithelial cadherin in the calcium bound state, NMR, 20 structures | solution nmr | A | — | — |
| 2OMW | Crystal structure of InlA S192N Y369S/mEC1 complex | x-ray diffraction | B | — | — |
| 2OMW | Crystal structure of inla S192N Y369S/MEC1 complex | x-ray diffraction | B | — | — |
| 2QVF | mouse E-cadherin domains 1,2 | x-ray diffraction | B | — | — |
| 2QVF | Mouse E-cadherin domains 1,2 | x-ray diffraction | B | — | — |
| 3IFQ | Interction of plakoglobin and beta-catenin with desmosomal cadherins | x-ray diffraction | C, D | — | — |
| 3IFQ | Interction of plakoglobin and beta-catenin with desmosomal cadherins | x-ray diffraction | C, D | — | — |
| 3LNE | Crystal structure of E-cadherin EC12 K14E | x-ray diffraction | A | — | — |
| 3LNE | Crystal structure of E-cadherin EC12 K14E | x-ray diffraction | A | — | — |
| 3LNF | Crystal structure of E-cadherin EC12 K14EW2A | x-ray diffraction | A, B | — | — |
| 3LNF | Crystal structure of E-cadherin EC12 K14EW2A | x-ray diffraction | A, B | — | — |
| 3LNG | Crystal structure of E-cadherin EC12 AA extension | x-ray diffraction | A, B | — | — |
| 3LNG | Crystal structure of E-cadherin EC12 aa extension | x-ray diffraction | A, B | — | — |
| 3LNH | Crystal structure of E-cadherin EC12 W2A | x-ray diffraction | A, B | — | — |
| 3LNH | Crystal structure of E-cadherin EC12 W2A | x-ray diffraction | A, B | — | — |
| 3LNI | Crystal structure of E-cadherin EC12 E89A | x-ray diffraction | A, B | — | — |
| 3LNI | Crystal structure of E-cadherin EC12 E89A | x-ray diffraction | A, B | — | — |
| 3Q2L | Mouse E-cadherin EC1-2 V81D mutant | x-ray diffraction | A, B | — | — |
| 3Q2L | Mouse E-cadherin EC1-2 V81D mutant | x-ray diffraction | A, B | — | — |
| 3Q2N | Mouse E-cadherin EC1-2 L175D mutant | x-ray diffraction | A, B | — | — |
| 3Q2N | Mouse E-cadherin EC1-2 L175D mutant | x-ray diffraction | A, B | — | — |
| 3Q2V | Crystal structure of mouse E-cadherin ectodomain | x-ray diffraction | A, B | — | — |
| 3Q2V | Crystal structure of mouse E-cadherin ectodomain | x-ray diffraction | A, B | — | — |
| 3QRB | crystal structure of E-cadherin EC1-2 P5A P6A | x-ray diffraction | A, B | — | — |
| 3QRB | Crystal structure of E-cadherin EC1-2 P5A P6A | x-ray diffraction | A, B | — | — |
| 4QD2 | Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex | x-ray diffraction | E, J | — | — |
| 4QD2 | Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin a complex | x-ray diffraction | E, J | — | — |
| 7AR4 | Crystal structure of beta-catenin in complex with cyclic peptide inhibitor | x-ray diffraction | PaP | — | 2 (best 0.60) |
| P09803 | AlphaFold monomer V2.0 prediction for cadherin-1 (P09803) | predicted | A | — | — |
Experiment against prediction
- 1EDH chain B against the predicted model P09803: TM-score 0.98, RMSD 0.70 Å
- 1EDH chain B against the predicted model P09803: TM-score 0.98, RMSD 0.70 Å
- 3LNI chain A against the predicted model P09803: TM-score 0.98, RMSD 0.78 Å
- 3LNI chain A against the predicted model P09803: TM-score 0.98, RMSD 0.78 Å
- 1EDH chain A against the predicted model P09803: TM-score 0.98, RMSD 0.77 Å
- 1EDH chain A against the predicted model P09803: TM-score 0.98, RMSD 0.77 Å
- 2QVF chain B against the predicted model P09803: TM-score 0.98, RMSD 0.77 Å
- 2QVF chain B against the predicted model P09803: TM-score 0.98, RMSD 0.77 Å
- 3LNH chain B against the predicted model P09803: TM-score 0.98, RMSD 0.77 Å
- 3LNH chain B against the predicted model P09803: TM-score 0.98, RMSD 0.77 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.