MolNFT v1 · #75106 · protein
Structure of sumoylated PCNA
3PGE · Sumo-modified proliferating cell nuclear antigen: “Structure of sumoylated PCNA”. X-ray diffraction, 3 pockets (best druggability 0.32). MolNFT v1 #75106 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3PGE
- Type
- protein
- Length
- 335 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sumo-modified proliferating cell nuclear antigen; Proliferating cell nuclear antigen
- UniProt
- Q12306, P15873
- Pockets
- 3 · best druggability 0.32
Structure
x-ray diffraction · 2 distinct chains · 18% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sumo-modified proliferating cell nuclear antigen | protein | 172 | 16% helix, 41% strand | Q12306, P15873 |
| B | Proliferating cell nuclear antigen | protein | 163 | 20% helix, 44% strand | P15873 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 88 | 0.32 | 0.73 | 24 | empty |
| 2 | 55 | 0.31 | 0.76 | 14 | empty |
| 3 | 58 | 0.28 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 2983 Ų buried · 58 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12306
- Every structure of UniProt P15873
- Elsewhere: RCSB PDB 3PGE · PDBe 3PGE · UniProt Q12306 · UniProt P15873
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