UniProt Q12306
Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase (Q12306)
Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase (UniProt Q12306), EC 2.7.1.59, 5.2.1.8: 73 experimental structures and 1 predicted model on GenesisL1, 22 ligands bound, 51 pockets. Binding sites, druggability and…
- UniProt
- Q12306
- Protein
- Ubiquitin-like protein SMT3,N-acetyl-D-glucosamine kinase
- EC
- 2.7.1.59, 5.2.1.8
- Experimental structures
- 73
- Predicted models
- 1
- Ligands
- 22
- Pockets
- 51 · 9 records with a druggable one
Structures
74 records of Q12306 in the MolNFT archive: 73 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1EUV | X-ray structure of the C-terminal ULP1 protease domain in complex with SMT3, the yeast ortholog of… | x-ray diffraction | B | — | — |
| 1EUV | X-ray structure of the C-terminal ULP1 protease domain in complex with SMT3, the yeast ortholog of… | x-ray diffraction | B | — | — |
| 1L2N | Smt3 Solution Structure | solution nmr | A | — | — |
| 1L2N | SMT3 solution structure | solution nmr | A | — | — |
| 2EKE | Structure of a SUMO-binding-motif mimic bound to Smt3p-Ubc9p: conservation of a noncovalent… | x-ray diffraction | C, D | — | — |
| 2EKE | Structure of a sumo-binding-motif mimic bound to SMT3P- UBC9P: conservation of a noncovalent… | x-ray diffraction | C, D | — | — |
| 3PGE | Structure of sumoylated PCNA | x-ray diffraction | A | — | — |
| 3PGE | Structure of sumoylated PCNA | x-ray diffraction | A | — | — |
| 3QHT | Crystal Structure of the Monobody ySMB-1 bound to yeast SUMO | x-ray diffraction | A, B | — | — |
| 3QHT | Crystal structure of the monobody ysmb-1 bound to yeast sumo | x-ray diffraction | A, B | — | — |
| 3TIX | Crystal structure of the Chp1-Tas3 complex core | x-ray diffraction | A, C | — | — |
| 3TIX | Crystal structure of the CHP1-TAS3 complex core | x-ray diffraction | A, C | — | — |
| 3UF8 | Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with a G95A surface mutation… | x-ray diffraction | A | — | — |
| 3UF8 | Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with a G95A surface mutation… | x-ray diffraction | A | — | — |
| 3UQA | Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation A54E… | x-ray diffraction | A | — | — |
| 3UQA | Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation A54E… | x-ray diffraction | A | — | — |
| 3UQB | Crystal structure of a SMT Fusion PEPTIDYL-PROLYL CIS-TRANS ISOMERASE with surface mutation D44G… | x-ray diffraction | A | — | — |
| 3UQB | Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation D44G… | x-ray diffraction | A | — | — |
| 3V60 | Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164 | x-ray diffraction | A | — | — |
| 3V60 | Structure of S. cerevisiae PCNA conjugated to sumo on lysine 164 | x-ray diffraction | A | — | — |
| 3V61 | Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164 | x-ray diffraction | A | — | — |
| 3V61 | Structure of S. cerevisiae PCNA conjugated to sumo on lysine 164 | x-ray diffraction | A | — | — |
| 3V62 | Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on… | x-ray diffraction | A, D | — | — |
| 3V62 | Structure of the S. cerevisiae SRS2 C-terminal domain in complex with PCNA conjugated to sumo on… | x-ray diffraction | A, D | — | — |
| 3VAW | Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation v3i… | x-ray diffraction | A | — | — |
| 3VAW | Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation V3I… | x-ray diffraction | A | — | — |
| 4FN2 | Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G… | x-ray diffraction | A, B | — | — |
| 4FN2 | Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation D44G… | x-ray diffraction | A, B | — | — |
| 4G50 | Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G… | x-ray diffraction | A, B | — | — |
| 4G50 | Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation D44G… | x-ray diffraction | A, B | — | — |
| 4GGQ | Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase from Burkholderia… | x-ray diffraction | C, A, B, D | — | — |
| 4GGQ | Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase from burkholderia… | x-ray diffraction | C, A, B, D | — | — |
| 4GIV | Crystal structure of a SMT fusion Peptidyl-prolyl cis-trans isomerase with surface mutation D44G… | x-ray diffraction | A, B | — | — |
| 4GIV | Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation D44G… | x-ray diffraction | A, B | — | — |
| 5D6J | Crystal structure of a mycobacterial protein | x-ray diffraction | B | — | — |
| 5JNE | E2-sumo-SIZ1 E3-sumo-PCNA complex | x-ray diffraction | A, C, E, G | — | — |
| 5KLX | Crystal Structure of SMT Fusion Peptidyl-Prolyl Cis-Trans Isomerase from Burkholderia Pseudomallei… | x-ray diffraction | A, B, C, D | 6UO, MG | — |
| 5KLX | Crystal structure of smt fusion peptidyl-prolyl cis-trans isomerase from burkholderia pseudomallei… | x-ray diffraction | A, B, C, D | 6UO, MG | — |
| 5V8T | Crystal structure of SMT fusion Peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei… | x-ray diffraction | A, B | 8ZV, MG | 3 (best 0.71) |
| 5V8T | Crystal structure of smt fusion peptidyl-prolyl cis-trans isomerase from burkholderia pseudomallei… | x-ray diffraction | A, B | 8ZV, MG | — |
| 5YC2 | Crystal structure of inner membrane protein BQT4 in complex with telomeric protein RAP1 | x-ray diffraction | A, C | — | — |
| 5YCA | Crystal structure of inner membrane protein BQT4 in complex with LEM2 | x-ray diffraction | A | — | — |
| 6CFP | Crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-SMITH/1933 (H1N1)… | x-ray diffraction | A | EZS | — |
| 6O49 | Crystal structure of smt fusion peptidyl-prolyl cis-trans isomerase from burkholderia pseudomallei… | x-ray diffraction | A, B | LL7, CA | — |
| 6O4A | Crystal structure of smt fusion peptidyl-prolyl cis-trans isomerase from burkholderia pseudomallei… | x-ray diffraction | A, B, C, D | CA, LLD | — |
| 6P81 | Structure of DNA polymerase III, beta subunit/ beta sliding clamp from klebsiella pneumoniae… | x-ray diffraction | A | ACE, CA, CL | — |
| 6Q2S | Cryo-EM structure of RET/GFRA3/ARTN extracellular complex. the 3D refinement was applied with C2… | electron microscopy | A, B | — | — |
| 6RPQ | Crystal structure of PHOCDC21-1 intein | x-ray diffraction | A | — | — |
| 6UKM | Sting C-terminal domain complexed with non-cyclic dinucleotide compound msa-2 | x-ray diffraction | A | QAD | — |
| 6UKU | Sting C-terminal domain complexed with non-cyclic dinucleotide compound 3 | x-ray diffraction | A | QAV | — |
| 6UKV | Sting C-terminal domain complexed with non-cyclic dinucleotide compound 9 | x-ray diffraction | A, B | QB1 | — |
| 6UKW | STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 10 | x-ray diffraction | A, B | QB7 | 1 (best 0.85) |
| 6UKW | Sting C-terminal domain complexed with non-cyclic dinucleotide compound 10 | x-ray diffraction | A, B | QB7 | — |
| 6UKX | STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 11 | x-ray diffraction | A, B | QBA | 1 (best 0.85) |
| 6UKX | Sting C-terminal domain complexed with non-cyclic dinucleotide compound 11 | x-ray diffraction | A, B | QBA | — |
| 6UKY | Sting C-terminal domain complexed with non-cyclic dinucleotide compound 12 | x-ray diffraction | A | QBD | — |
| 6UKZ | Sting C-terminal domain complexed with non-cyclic dinucleotide compound 6 | x-ray diffraction | A, B | QBG | — |
| 6UL0 | Sting C-terminal domain complexed with non-cyclic dinucleotide compound 4 | x-ray diffraction | A | QBJ | — |
| 6VEL | Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody 66E8Fab | x-ray diffraction | C | SO4, CA | 3 (best 0.61) |
| 6VEL | Crystal structure of human E-cadherin bound by mouse monoclonal antibody 66E8FAB | x-ray diffraction | C | SO4, CA | — |
14 records more on the page itself.
Ligands
- CA · Calcium ion · in 5 records
- MG · Magnesium ion · in 4 records
- CL · Chloride ion · in 3 records
- ZN · Zinc ion · in 3 records
- 6UO · 2-[(2~{S})-1-(phenylmethyl)sulfonylpiperidin-2-yl]carbonyloxyethyl pyridine-3-carboxylate · in 2 records
- 8ZV · 2-{[3,5-bis(2-methoxyethoxy)benzene-1-carbonyl]amino}ethyl (2S)-1-(benzylsulfonyl) piperidine-2-carboxylate · in 2 records
- QB7 · 4-[6-(3-{[2-(3-carboxypropanoyl)-4-fluoro-6-methoxy-1-benzothiophen-5-yl]oxy}propoxy)-5-methoxy-1-benzothiophen-2-yl]-4-oxobutanoic acid · in 2 records
- QBA · 4,4'-{propane-1,3-diylbis[oxy(5-methoxy-1-benzothiene-6,2-diyl)]}bis(4-oxobutanoic acid) · in 2 records
- SO4 · Sulfate ion · in 2 records
- ACE · Acetyl group · in 1 record
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 1 record
- EZS · 1-{1-[(4-fluorophenyl)methyl]-2-methyl-1H-imidazol-4-yl}ethan-1-one · in 1 record
- K · Potassium ion · in 1 record
- LL7 · (2~{S})-~{N}-[3-oxidanylidene-3-[(3,4,5-trimethoxyphenyl)amino]propyl]-1-(phenylmethyl) sulfonyl-piperidine-2-carboxamide · in 1 record
- LLD · 2-(pyridin-3-ylcarbonylamino)ethyl (2~{S})-1-(phenylmethyl)sulfonylpiperidine-2-carboxylate · in 1 record
- NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose · in 1 record
- QAD · 4-(5,6-dimethoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid · in 1 record
- QAV · 4,4'-[propane-1,3-diylbis(6-methoxy-1-benzothiene-5,2-diyl)]bis(4-oxobutanoic acid) · in 1 record
- QB1 · 4-[6-(3-{[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-5-yl]oxy}propoxy)-5-methoxy-1-benzothiophen-2-yl]-4-oxobutanoic acid · in 1 record
- QBD · 4-(6-{3-[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-4-yl]propyl}-5-methoxy-1-benzothiophen-2-yl)-4-oxobutanoic acid · in 1 record
- QBG · 4-[5-(2-{[2-(3-carboxypropanoyl)-4-fluoro-6-methoxy-1-benzothiophen-5-yl]oxy}ethoxy)-6-methoxy-1-benzothiophen-2-yl]-4-oxobutanoic acid · in 1 record
- QBJ · 4-{5-[(1Z)-3-{[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-5-yl]oxy}prop-1-en-1-yl]-6-methoxy-1-benzothiophen-2-yl}-4-oxobutanoic acid · in 1 record
Experiment against prediction
- 6VEL chain C against the predicted model P12830: TM-score 0.98, RMSD 0.82 Å
- 6VEL chain C against the predicted model P12830: TM-score 0.98, RMSD 0.82 Å
- 5D6J chain B against the predicted model Q12306: TM-score 0.97, RMSD 0.51 Å
- 3QHT chain B against the predicted model Q12306: TM-score 0.97, RMSD 0.52 Å
- 3QHT chain B against the predicted model Q12306: TM-score 0.97, RMSD 0.52 Å
- 6Q2S chain A against the predicted model Q5T4W7: TM-score 0.96, RMSD 0.72 Å
- 6Q2S chain B against the predicted model Q5T4W7: TM-score 0.96, RMSD 0.72 Å
- 3V61 chain A against the predicted model Q12306: TM-score 0.95, RMSD 0.81 Å
- 3V61 chain A against the predicted model Q12306: TM-score 0.95, RMSD 0.81 Å
- 7SDE chain B against the predicted model P40026: TM-score 0.94, RMSD 1.52 Å
Elsewhere
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