MolNFT v1 · #74310 · protein
Crystal structure of the complex of proteinase K with an antimicrobial nonapeptide, at 2.26 a resolution
3OSZ: “Crystal structure of the complex of proteinase K with an antimicrobial nonapeptide, at 2.26 a resolution”. X-ray diffraction, 2 ligands (CA, NO3), 1 pocket (best druggability 0.46). MolNFT v1 #74310 on GenesisL1: 3D structure…
- PDB
- 3OSZ
- Type
- protein
- Length
- 289 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Proteinase K; 10-mer peptide
- EC
- 3.4.21.64
- UniProt
- P06873
- Ligands
- CA, NO3
- Pockets
- 1 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 26% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proteinase K (EC 3.4.21.64) | protein | 279 | 27% helix, 24% strand | P06873 |
| B | 10-mer peptide | protein | 10 | 0% helix, 0% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 101 | 0.46 | 0.80 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 561 Ų buried · 11 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 3OSZ · Crystal Structure of the complex of proteinase K with an antimicrobial nonapeptide, at… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06873
- Elsewhere: RCSB PDB 3OSZ · PDBe 3OSZ · UniProt P06873
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