MolNFT v1 · #5812 · protein
The crystal structure of E. COLI fis mutant R71Y
1ETQ · Factor for inversion stimulation: “The crystal structure of E. COLI fis mutant R71Y”. X-ray diffraction, 2 pockets (best druggability 0.48). MolNFT v1 #5812 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1ETQ
- Type
- protein
- Length
- 319 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Factor for inversion stimulation
- UniProt
- P0A6R3
- Pockets
- 2 · best druggability 0.48
Structure
x-ray diffraction · 4 distinct chains · 66% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Factor for inversion stimulation | protein | 85 | 61% helix, 7% strand | P0A6R3 |
| B | Factor for inversion stimulation | protein | 76 | 67% helix, 5% strand | P0A6R3 |
| C | Factor for inversion stimulation | protein | 77 | 69% helix, 3% strand | P0A6R3 |
| D | Factor for inversion stimulation | protein | 81 | 67% helix, 5% strand | P0A6R3 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 191 | 0.48 | 0.76 | 24 | empty |
| 2 | 68 | 0.31 | 0.74 | 15 | empty |
Interfaces
3 interfaces between chains.
- C–D · 2144 Ų buried · 18 hydrogen bonds · protein-protein
- A–B · 2140 Ų buried · 21 hydrogen bonds · protein-protein
- B–D · 122 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A6R3
- Elsewhere: RCSB PDB 1ETQ · PDBe 1ETQ · UniProt P0A6R3
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