MolNFT v1 · #58081 · protein
Structure of UHRF1 in complex with histone tail
3ASL · E3 ubiquitin-protein ligase UHRF1: “Structure of UHRF1 in complex with histone tail”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #58081 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3ASL
- Type
- protein
- Length
- 77 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E3 ubiquitin-protein ligase UHRF1; Histone H3.3
- EC
- 6.3.2.-
- UniProt
- Q96T88, P84243
- Ligands
- ZN
Structure
x-ray diffraction · 2 distinct chains · 8% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase UHRF1 (EC 6.3.2.-) | protein | 68 | 9% helix, 10% strand | Q96T88 |
| B | Histone H3.3 | protein | 9 | 0% helix, 11% strand | P84243 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 475 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 3ASL · Structure of UHRF1 in complex with histone tail · the same entry in another collection · chain A against A, TM-score 1.00
- Q96T88 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase UHRF1 (Q96T88) · a predicted model of the same protein · chain A against A, TM-score 0.93
- P84243 · AlphaFold monomer V2.0 prediction for histone H3.3 (P84243) · a predicted model of the same protein · chain B against A, TM-score 0.41
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96T88
- Every structure of UniProt P84243
- Elsewhere: RCSB PDB 3ASL · PDBe 3ASL · UniProt Q96T88 · UniProt P84243
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