MolNFT v1 · #53057 · protein

Crystal structure of the tyrosine phosphatase wzb from escherichia COLI K30 in complex with phosphate.

2WJA · Putative acid phosphatase wzb: “Crystal structure of the tyrosine phosphatase wzb from escherichia COLI K30 in complex with phosphate.”. X-ray diffraction, 2 ligands (NI, PO4), 1 pocket (best druggability 0.46). MolNFT v1 #53057 on…

PDB: 2WJA
Type: protein
Length: 284 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative acid phosphatase wzb
UniProt: Q9X4B8
Ligands: NI, PO4
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 2 distinct chains · 40% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative acid phosphatase wzb	protein	146	41% helix, 14% strand	Q9X4B8
B	Putative acid phosphatase wzb	protein	138	39% helix, 16% strand	Q9X4B8

Ligands and binding sites

NI · Nickel (II) ion · metal · chains A
PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	100	0.46	0.80	15	empty

Interfaces

1 interface between chains.

A–B · 277 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

2WJA · Crystal structure of the tyrosine phosphatase Wzb from Escherichia coli K30 in complex… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9X4B8
Elsewhere: RCSB PDB 2WJA · PDBe 2WJA · UniProt Q9X4B8

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