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Crystal structure of the tyrosine phosphatase wzb from escherichia COLI K30 in complex with phosphate.

Analyse Crystal structure of the tyrosine phosphatase wzb from escherichia COLI K30 in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2WJA
Type: protein
Length: 284 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative acid phosphatase wzb
UniProt: Q9X4B8
Ligands: NI, PO4
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 2 distinct chains · 40% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative acid phosphatase wzb	protein	146	41% helix, 14% strand	Q9X4B8
B	Putative acid phosphatase wzb	protein	138	39% helix, 16% strand	Q9X4B8

Ligands and binding sites

NI · Nickel (II) ion · metal · chains A
PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	100	0.46	0.80	15	empty

Interfaces

1 interface between chains.

A–B · 277 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

2WJA · Crystal structure of the tyrosine phosphatase Wzb from Escherichia coli K30 in complex… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9X4B8
Elsewhere: RCSB PDB 2WJA · PDBe 2WJA · UniProt Q9X4B8

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