GL1X · GenesisL1 explorer

MolNFT v1 · #52441 · protein

GRB2 SH3C (3)

2W0Z · Growth factor receptor-bound protein 2: “GRB2 SH3C (3)”. X-ray diffraction. MolNFT v1 #52441 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2W0Z
Type
protein
Length
67 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Growth factor receptor-bound protein 2; GRB2-associated-binding protein 2
UniProt
P62993, Q9UQC2

Structure

x-ray diffraction · 2 distinct chains · 4% helix, 43% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGrowth factor receptor-bound protein 2protein585% helix, 50% strandP62993
BGRB2-associated-binding protein 2protein90% helix, 0% strandQ9UQC2

Interfaces

1 interface between chains.

  • A–B · 481 Ų buried · 7 hydrogen bonds · protein-protein

Compared structures

  • 2W0Z · Grb2 SH3C (3) · the same entry in another collection · chain A against A, TM-score 1.00
  • P62993 · AlphaFold monomer V2.0 prediction for growth factor receptor-bound protein 2 (P62993) · a predicted model of the same protein · chain A against A, TM-score 0.94
  • Q9UQC2 · AlphaFold monomer V2.0 prediction for GRB2-associated-binding protein 2 (Q9UQC2) · a predicted model of the same protein · chain B against A, TM-score 0.52

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