UniProt Q9UQC2
Q9UQC2
Q9UQC2 (UniProt Q9UQC2): 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UQC2
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
Structures
8 records of Q9UQC2 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2VWF | Grb2 SH3C (2) | x-ray diffraction | B | — | — |
| 2VWF | GRB2 SH3C (2) | x-ray diffraction | B | — | — |
| 2W0Z | Grb2 SH3C (3) | x-ray diffraction | B | — | — |
| 2W0Z | GRB2 SH3C (3) | x-ray diffraction | B | — | — |
| 5EWZ | Small-molecule stabilization of the 14-3-3/GAB2 ppi interface | x-ray diffraction | C, D | — | — |
| 5EXA | Small-molecule stabilization of the 14-3-3/Gab2 PPI interface | x-ray diffraction | C, D | 5SO | — |
| 5EXA | Small-molecule stabilization of the 14-3-3/GAB2 ppi interface | x-ray diffraction | C, D | — | — |
| Q9UQC2 | AlphaFold monomer V2.0 prediction for GRB2-associated-binding protein 2 (Q9UQC2) | predicted | A | — | — |
Ligands
- 5SO · Fusicoccin A-THF derivative · in 1 record
Experiment against prediction
- 5EWZ chain D against the predicted model Q9UQC2: TM-score 0.69, RMSD 0.37 Å
- 2W0Z chain B against the predicted model Q9UQC2: TM-score 0.52, RMSD 0.88 Å
- 2W0Z chain B against the predicted model Q9UQC2: TM-score 0.52, RMSD 0.88 Å
- 5EXA chain C against the predicted model Q9UQC2: TM-score 0.43, RMSD 0.65 Å
- 5EXA chain C against the predicted model Q9UQC2: TM-score 0.43, RMSD 0.65 Å
- 5EWZ chain C against the predicted model Q9UQC2: TM-score 0.40, RMSD 0.85 Å
- 5EXA chain D against the predicted model Q9UQC2: TM-score 0.37, RMSD 0.80 Å
- 5EXA chain D against the predicted model Q9UQC2: TM-score 0.37, RMSD 0.80 Å
- 2VWF chain B against the predicted model Q9UQC2: TM-score 0.34, RMSD 1.89 Å
- 2VWF chain B against the predicted model Q9UQC2: TM-score 0.34, RMSD 1.89 Å
Elsewhere
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