MolNFT v1 · #50811 · protein
Solution structure of the complex between P53 transactivation domain 2 and tfiih P62 pH domain
2RUK · Cellular tumor antigen P53: “Solution structure of the complex between P53 transactivation domain 2 and tfiih P62 pH domain”. Solution nmr. MolNFT v1 #50811 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2RUK
- Type
- protein
- Length
- 130 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cellular tumor antigen P53; General transcription factor iih subunit 1
- UniProt
- P04637, P32780
Structure
solution nmr · 2 distinct chains · 17% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cellular tumor antigen P53 | protein | 22 | 14% helix, 0% strand | P04637 |
| B | General transcription factor iih subunit 1 | protein | 108 | 18% helix, 43% strand | P32780 |
Interfaces
1 interface between chains.
- A–B · 1012 Ų buried · 36 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (phosphorylation).
Compared structures
- 2RUK · Solution structure of the complex between p53 transactivation domain 2 and TFIIH p62 PH… · the same entry in another collection · chain A against A, TM-score 1.00
- P32780 · AlphaFold monomer V2.0 prediction for general transcription factor iih subunit 1 (P32780) · a predicted model of the same protein · chain B against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04637
- Every structure of UniProt P32780
- Elsewhere: RCSB PDB 2RUK · PDBe 2RUK · UniProt P04637 · UniProt P32780
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