Myrosinase from sinapis alba with a bound transition state ANALOGUE,D- glucono-1,5-lactone

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 18% strand (DSSP).

Ligands and binding sites

• LGC · D-glucono-1,5-lactone · ligand · chains M
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 12 copies · chains M
• BMA · beta-D-mannopyranose · sugar · 2 copies
• XYP · beta-D-xylopyranose · sugar · 2 copies
• FUC · alpha-L-fucopyranose · sugar · 2 copies · chains M
• MAN · alpha-D-mannopyranose · sugar · chains M
• ZN · Zinc ion · metal · chains M
• SO4 · Sulfate ion · ion · 8 copies · chains M
• GOL · Glycerol · additive · 4 copies · chains M

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 9 glycan, 3 disulfide (N-glycosylation, disulfide).

Compared structures

• 1E6X · MYROSINASE FROM SINAPIS ALBA with a bound transition state analogue,D-glucono-1,5-lactone · the same entry in another collection · chain M against M, TM-score 1.00
• P29736 · AlphaFold monomer V2.0 prediction for myrosinase MA1 (P29736) · a predicted model of the same protein · chain M against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P29736
• Elsewhere: RCSB PDB 1E6X · PDBe 1E6X · UniProt P29736