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Ligand · LGC

LGC · D-glucono-1,5-lactone

LGC, D-glucono-1,5-lactone (C6 H10 O6, 178.1 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
LGC
Formula
C6 H10 O6
Class
ligand
Structures
5
PDB entries
4

Binding sites

LGC in 5 structures; the first of them:

  • 4YNU · Crystal structure of Aspergillus flavus FADGDH in complex with D-glucono-1,5-lactone · LGC A602 · binds TYR53, GLY94, MET95, ASN318, LEU401, GLU413, TRP415, ARG501 and 4 more
  • 7D6B · Crystal structure of Oryza sativa Os4BGlu18 monolignol beta-glucosidase with… · LGC A601 · binds GLN46, HIS148, TYR149, ASN193, GLU194, TYR265, ASN335, TYR337 and 7 more
  • 7VKF · Reduced enzyme of FAD-dpendent Glucose Dehydrogenase complex with D-glucono-1,5-lactone… · LGC A601 · binds TYR54, GLY95, ALA97, ASN319, LEU402, GLU414, TRP416, ARG502 and 3 more
  • 5XXM · Crystal structure of GH3 beta-glucosidase from bacteroides thetaiotaomicron in complex… · LGC A802 · binds THR59, PHE80, ASP110, PHE154, ARG168, LYS207, HIS208, MET251 and 5 more
  • 7D6B · Crystal structure of oryza sativa OS4BGLU18 monolignol beta- glucosidase with… · LGC A601 · binds GLN46, HIS148, TYR149, ASN193, GLU194, ASN335, TYR337, MET378 and 5 more

Residues it binds most

GLU 8, TYR 9, ASN 7, PHE 7, HIS 8, TRP 6, MET 7, ARG 5, ASP 2, GLN 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • GOL · Glycerol
  • FAD · Flavin-adenine dinucleotide
  • FDA · Dihydroflavine-adenine dinucleotide
  • MG · Magnesium ion
  • B3P · 2-[3-(2-hydroxy-1,1-dihydroxymethyl-ethylamino)-propylamino]-2-hydroxymethyl-propane-1,3-diol
  • PG4 · Tetraethylene glycol

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