MolNFT v1 · #49639 · protein

Crystal structure of lipa from serratia marcescens

2QUA · Extracellular lipase: “Crystal structure of lipa from serratia marcescens”. X-ray diffraction, 1 ligand (CA), 7 pockets (best druggability 0.71). MolNFT v1 #49639 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2QUA
Type: protein
Length: 615 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Extracellular lipase
EC: 3.1.1.3
UniProt: Q59933
Ligands: CA
Pockets: 7 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Extracellular lipase (EC 3.1.1.3)	protein	615	26% helix, 26% strand	Q59933

Ligands and binding sites

CA · Calcium ion · metal · 8 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	536	0.71	0.79	42	empty
2	265	0.56	0.77	36	empty
3	74	0.51	0.85	17	empty
4	171	0.50	0.77	32	empty
5	88	0.45	0.81	24	empty

Compared structures

2QUA · Crystal structure of LipA from Serratia marcescens · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q59933
Elsewhere: RCSB PDB 2QUA · PDBe 2QUA · UniProt Q59933

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