MolNFT v1 · #49464 · protein
Crystal structure of plasmodium vivax guanylate kinase
2QOR: “Crystal structure of plasmodium vivax guanylate kinase”. X-ray diffraction, 2 ligands (5GP, POP), 1 pocket (best druggability 0.68). MolNFT v1 #49464 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2QOR
- Type
- protein
- Length
- 196 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Guanylate kinase
- EC
- 2.7.4.8
- UniProt
- A5K709
- Ligands
- 5GP, POP
- Pockets
- 1 · best druggability 0.68
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Guanylate kinase (EC 2.7.4.8) | protein | 196 | 42% helix, 21% strand | A5K709 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 392 | 0.68 | 0.81 | 42 | 5GP, POP |
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 2QOR · Crystal structure of Plasmodium vivax guanylate kinase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5K709
- Elsewhere: RCSB PDB 2QOR · PDBe 2QOR · UniProt A5K709
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