MolNFT v1 · #49114 · protein
Crystal structure of a putative metal-dependent hydrolase (yiza, BSU10800) from bacillus subtilis at 1.90 a resolution
2QE9 · Uncharacterized protein yiza: “Crystal structure of a putative metal-dependent hydrolase (yiza, BSU10800) from bacillus subtilis at 1.90 a…”. X-ray diffraction, 1 ligand (NI), 2 pockets (best druggability 0.31). MolNFT v1 #49114 on…
- PDB
- 2QE9
- Type
- protein
- Length
- 327 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein yiza
- UniProt
- Q7WY73
- Ligands
- NI
- Pockets
- 2 · best druggability 0.31
Structure
x-ray diffraction · 2 distinct chains · 61% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein yiza | protein | 165 | 61% helix, 2% strand | Q7WY73 |
| B | Uncharacterized protein yiza | protein | 162 | 60% helix, 4% strand | Q7WY73 |
Ligands and binding sites
- NI · Nickel (II) ion · metal · 2 copies · chains A, B
- CIT · Citric acid · additive · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 83 | 0.31 | 0.74 | 18 | EDO |
| 2 | 59 | 0.31 | 0.76 | 20 | CIT |
Interfaces
1 interface between chains.
- A–B · 1592 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 2QE9 · Crystal structure of a putative metal-dependent hydrolase (yiza, bsu10800) from bacillus… · the same entry in another collection · chain A against A, TM-score 1.00
- Q7WY73 · AlphaFold monomer V2.0 prediction for uncharacterized protein yiza (Q7WY73) · a predicted model of the same protein · chain B against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7WY73
- Elsewhere: RCSB PDB 2QE9 · PDBe 2QE9 · UniProt Q7WY73
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.