Crystallographic structure of phosphorylated pilin from neisseria: phosphoserine sites modify type IV pilus surface chemistry

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 25% strand (DSSP).

Ligands and binding sites

• HTO · Heptane-1,2,3-triol · ligand · chains A
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
• GLA · alpha-D-galactopyranose · sugar
• PT · Platinum (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 2 modified, 1 disulfide, 1 glycan (disulfide, O-glycosylation, nonstandard, phosphorylation).

Compared structures

• 2PIL · Crystallographic Structure of Phosphorylated Pilin from Neisseria: Phosphoserine Sites… · the same entry in another collection · chain A against A, TM-score 1.00
• P02974 · AlphaFold monomer V2.0 prediction for type IV major pilin protein PILE1 (P02974) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P02974
• Elsewhere: RCSB PDB 2PIL · PDBe 2PIL · UniProt P02974