MolNFT v1 · #44044 · protein
Solution structure of human 53BP1 tandem tudor domains in complex with a histone H4K20ME2 peptide
2LVM · Tumor suppressor P53-binding protein 1: “Solution structure of human 53BP1 tandem tudor domains in complex with a histone H4K20ME2 peptide”. Solution nmr. MolNFT v1 #44044 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2LVM
- Type
- protein
- Length
- 137 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tumor suppressor P53-binding protein 1; Histone H4
- UniProt
- Q12888, P62805
Structure
solution nmr · 2 distinct chains · 12% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tumor suppressor P53-binding protein 1 | protein | 123 | 14% helix, 52% strand | Q12888 |
| B | Histone H4 | protein | 14 | 0% helix, 0% strand | P62805 |
Interfaces
1 interface between chains.
- A–B · 765 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (methylation).
Compared structures
- 2LVM · Solution structure of human 53BP1 tandem Tudor domains in complex with a histone H4K20me2… · the same entry in another collection · chain A against A, TM-score 1.00
- Q12888 · AlphaFold monomer V2.0 prediction for TP53-binding protein 1 (Q12888) · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12888
- Every structure of UniProt P62805
- Elsewhere: RCSB PDB 2LVM · PDBe 2LVM · UniProt Q12888 · UniProt P62805
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