MolNFT v1 · #43780 · protein

Solution structure of ca-bound S100A4 in complex with non-muscle myosin iia

2LNK · Myosin heavy chain, non-muscle iia: “Solution structure of ca-bound S100A4 in complex with non-muscle myosin iia”. Solution nmr. MolNFT v1 #43780 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2LNK
Type: protein
Length: 241 residues
Chains: 3
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myosin heavy chain, non-muscle iia; Protein S100-A4
UniProt: P35579, P26447

Structure

solution nmr · 2 distinct chains · 56% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
C	Myosin heavy chain, non-muscle iia	protein	39	56% helix, 0% strand	P35579
A, B	Protein S100-A4	protein	101	55% helix, 2% strand	P26447

Interfaces

3 interfaces between chains.

A–B · 1575 Å² buried · 10 hydrogen bonds · protein-protein
C–B · 1307 Å² buried · 14 hydrogen bonds · protein-protein
C–A · 994 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

2LNK · Solution structure of Ca-bound S100A4 in complex with non-muscle myosin IIA · the same entry in another collection · chain C against C, TM-score 1.00
P26447 · AlphaFold monomer V2.0 prediction for protein S100-A4 (P26447) · a predicted model of the same protein · chain A against A, TM-score 0.73
P35579 · AlphaFold monomer V2.0 prediction for myosin-9 (P35579) · a predicted model of the same protein · chain C against A, TM-score 0.54

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35579
Every structure of UniProt P26447
Elsewhere: RCSB PDB 2LNK · PDBe 2LNK · UniProt P35579 · UniProt P26447

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